PLoS Genetics Turns Three: Looking Back, Looking Ahead

PLoS Genetics Turns Three: Looking Back, Looking Ahead

PLoS Genetics is three years old this month—a milestone worth celebrating! As we do, and as we recognize all who have helped us reach this point in time, we thought this would be a good opportunity to share with you a summary of our brief history and a look ahead. Our original intent was to provide an open-access journal for the community that would ‘‘reflect the full breadth and interdisciplin...

Stunting in Nepal: looking back, looking ahead†

Nepal hasmade impressive gains in health and nutrition despite being in a state of political, economic and demographic transition. According to the Nepal Demographic Health Surveys, stunting in Nepal has fallen from 57% in 2001 to 41% in 2011, an annual decline of 1.7 percentage points. A 3.9% annual reduction is, however, required to achieve the global target of 40% fewer stunted children by 2...

Neoepitopes of Cancers: Looking Back, Looking Ahead.

The search for specificity in cancers has been a holy grail in cancer immunology. Cancer geneticists have long known that cancers harbor transforming and other mutations. Immunologists have long known that inbred mice can be immunized against syngeneic cancers, indicating the existence of cancer-specific antigens. With the technological advances in high-throughput DNA sequencing and bioinformat...

Tobacco quitlines: looking back and looking ahead.

Telephone based tobacco cessation services, or quitlines, have become central components of many comprehensive tobacco control programmes. This paper provides an overview of their history, noting milestones in the growth of quitlines. Key factors in their worldwide adoption were solid evidence from clinical trials with large community samples and strong backing from public health officials. Qui...

Disabilities: looking back and looking ahead.